In Netflix’s The Fall of the House of Usher helmed by Mike Flanagan, the Usher family has made billions from their pharmaceutical company Fortunato. But just because they own a drug company doesn’t mean that they themselves can escape the ravages of disease. Head of the family Roderick Usher admits that he has been diagnosed with vascular dementia, specifically a rare form known by the acronym CADASIL. It turns out that this malady is generational, as it also afflicted Roderick’s mother, Eliza.Rarely is anything as notable as a familial disease incidental in good filmmaking, so what is Mike Flanagan trying to say with vascular dementia in The Fall of the House of Usher? A billionaire with a failing heart and mind spells doom for the entire Usher line not only physically but metaphorically. And why are the hearts of the Ushers of interest to the shape-shifting creature, Verna?In general, vascular dementia refers to the lack of cognitive abilities and function that are a result of decreased blood flow to the brain. This lack of blood flow means that the brain is not receiving the amount of oxygen that it requires, so cell death and brain damage ensue. This is a common side effect of stroke, Alzheimer’s, or any number of conditions that affect blood vessel health. If for one reason or another not enough blood is reaching the brain, then dementia is likely to be a symptom. In the case of the inherited condition known as cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, or CADASIL for short, the walls of smaller blood vessel walls thicken, which blocks blood flow to the brain. The vascular muscles also weaken and die. This cell death is known as an infarct. Strokes are much more likely in areas with infarcts, leading to even more cognitive impairment, mood and personality changes, and overall brain damage.RELATED: Netflix’s The Fall of the House of Usher’s Big Reveal Carries a Bigger Message
In Netflix’s The Fall of the House of Usher helmed by Mike Flanagan, the Usher family has made billions from their pharmaceutical company Fortunato. But just because they own a drug company doesn’t mean that they themselves can escape the ravages of disease. Head of the family Roderick Usher admits that he has been diagnosed with vascular dementia, specifically a rare form known by the acronym CADASIL. It turns out that this malady is generational, as it also afflicted Roderick’s mother, Eliza.
Rarely is anything as notable as a familial disease incidental in good filmmaking, so what is Mike Flanagan trying to say with vascular dementia in The Fall of the House of Usher? A billionaire with a failing heart and mind spells doom for the entire Usher line not only physically but metaphorically. And why are the hearts of the Ushers of interest to the shape-shifting creature, Verna?
In general, vascular dementia refers to the lack of cognitive abilities and function that are a result of decreased blood flow to the brain. This lack of blood flow means that the brain is not receiving the amount of oxygen that it requires, so cell death and brain damage ensue. This is a common side effect of stroke, Alzheimer’s, or any number of conditions that affect blood vessel health. If for one reason or another not enough blood is reaching the brain, then dementia is likely to be a symptom. In the case of the inherited condition known as cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, or CADASIL for short, the walls of smaller blood vessel walls thicken, which blocks blood flow to the brain. The vascular muscles also weaken and die. This cell death is known as an infarct. Strokes are much more likely in areas with infarcts, leading to even more cognitive impairment, mood and personality changes, and overall brain damage.
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